Impact of the COVID-19 pandemic on the gingival health of children and adolescents with cerebral palsy / Impacto da pandemia do COVID-19 na saúde gengival de crianças e adolescentes com paralisia cerebral

Objective: to evaluate the impact of the COVID-19 pandemic on children and adolescents with cerebral palsy, comparing the gingival condition and the type of dental treatment before and after the interruption of dental care. Material and Methods: the retrospective longitudinal study consisted of 273 participants undergoing Dental Clinic of the AACD (Disabled Child Assistance Association), divided into three groups according to age: Group 1 (G1: 0 to 5 years and 11 months; n=137), Group 2 (G2: 6 to 11 years and 11 months; n=85) and Group 3 (G3: 12 to 17 years and 11 months; n=51). Sociodemographic, data, clinical pattern of cerebral palsy and use of medication were collected, evaluating the gingival condition by the gingival index and the type of dental treatment before the pandemic and during, nine months after the interruption of dental care. Chi-square, Fisher Exact and Kruskal-Wallis (α=5%) tests were used. Results: the groups were homogeneous in terms of sex (p=0.4581), race (p=0.1725), clinical pattern (p=0.3482) and use of antiepileptic drugs (p=0.3509). Regarding the gingival condition, in the period during the pandemic, there was a reduction in the number of participants with Gingival Index scores 0 and 1 and an increase in participants with scores 2 and 3 (p<0.05). As for the procedures performed, the three groups showed a reduction in preventive procedures (p<0.05) and an increase in surgical, periodontal and restorative procedures (p<0.05). Conclusion: it is concluded that the interruption of dental care for nine months during the COVID-19 pandemic in children and adolescents with cerebral palsy had a negative impact on oral health (AU)

Objetivo: avaliar o impacto da pandemia da COVID-19 em crianças e adolescentes com Paralisia Cerebral, comparando a condição gengival e o tipo de tratamento odontológico antes e após a interrupção dos atendimentos odontológicos. Material e Métodos: o estudo longitudinal retrospectivo foi composto por 273 participantes atendidos na Clínica odontológica da AACD (Associação de Assistência à Criança Deficiente), reunidos em três grupos segundo a faixa etária: Grupo 1 (G1: 0 a 5 anos e 11 meses; n=137), Grupo 2 (G2: 6 a 11 anos e 11 meses; n=85) e Grupo 3 (G3: 12 a 17 anos e 11 meses; n=51). Foram coletados dados sociodemográficos, padrão clínico da Paralisia Cerebral e o uso de medicação, avaliando a condição gengival pelo índice gengival e o tipo de tratamento odontológico antes e durante a pandemia, nove meses após a interrupção dos atendimentos. Foram empregados os testes Qui-quadrado, Exato de Fisher e Kruskal-Wallis (α=5%). Resultados: os grupos eram homogêneos quanto ao sexo (p=0,4581), raça (p=0,1725), padrão clínico (p=0,3482) e uso de drogas antiepiléticas (p=0,3509). Com relação à condição gengival, no período Durante Pandemia, observou-se redução no número de participantes com escores Índice Gengival 0 e 1 e aumento de participantes com escores 2 e 3 (p<0,05). Quanto aos procedimentos realizados, os três grupos apresentaram redução de procedimentos preventivos (p<0,05) e aumento dos procedimentos cirúrgicos, periodontal e restaurador (p<0,05). Conclusão: conclui-se que a interrupção do acompanhamento odontológico por nove meses na pandemia da COVID-19 em crianças e adolescentes com PC acarretou impacto negativo na saúde bucal (AU)

Dental care for patients with special needs at a private higher education institute / Atendimento odontológico a pacientes com necessidades especiais em uma instituição privada de ensino superior

Objetivo: Pacientes com necessidades especiais são aqueles indivíduos que necessitam de cuidados especiais por tempo indeterminado ou por toda a vida. O presente estudo tem como objetivo abordar o atendimento odontológico de pacientes com necessidades especiais em uma instituição privada de ensino superior da cidade de São Paulo. Material e Métodos: Foi realizado um estudo descritivo, retrospectivo, para análise de 210 prontuários odontológicos de pacientes com necessidades especiais atendidos no Departamento de Odontologia para Pacientes Especiais da Universidade Cruzeiro do Sul entre 2012 e 2018. Dados sobre sexo, idade, diagnóstico da condição debilitante, motivo da consulta, uso continuado de medicamentos, imagens radiográficas e tratamentos odontológicos prestados foram todos coletados e posteriormente submetidos à análise estatística descritiva e inferencial (teste do qui-quadrado) ao nível de significância de 5%. Resultados: Quanto aos tipos de procedimentos odontológicos avaliados no presente estudo, dos 210 pacientes, 24% necessitaram de tratamentos curativos dentários em que a terapia periodontal foi o tipo mais prevalente, enquanto os tratamentos endodônticos tiveram a menor prevalência, representando apenas 4%. Houve alta prevalência de doenças crônicas sistêmicas, acometendo 56% dos casos, cuja faixa etária era superior a 40 anos. Conclusão: Check-ups odontológicos regulares devem ser priorizados em pacientes com necessidades especiais para evitar intervenções mais invasivas como em nosso grupo (AU)

Objective: Patients with special needs are those individuals who need special care for an undetermined period of time or for lifetime. The present study is aimed to address the dental care of special needs patients at a private higher education institute in the city of São Paulo. Material and Methods: A descriptive, retrospective study was performed for analysis of 210 dental records of special needs patients who were treated at the Dental Department for Special Patients of the Cruzeiro do Sul University between 2012 and 2018. Data on gender, age, diagnosis of the debilitating condition, reason of the consultation, continued use of medications, radiographic images and dental treatments provided were all collected before being submitted to descriptive and inferential statistical analysis (chi-square test) at a significance level of 5%. Results: As for the types of dental procedures assessed in the present study, of the 210 patients, 24% needed dental curative treatments in which periodontal therapy was the most prevalent type, whereas endodontic treatments had the lowest prevalence, representing 4% only. There was a high prevalence of chronic systemic diseases, affecting 56% of the dental records, whose age group was above 40 years old. Conclusion: Regular dental check-ups should be prioritized in patients with special needs to avoid more invasive interventions as found in our group (AU)

Shprintzen-goldberg craniosynostosis: craniofacial and oral characteristics, diagnosis, and clinical management of a very rare syndrome / Craniossinostose de shprintzen-goldberg: características craniofaciais e orais, diagnóstico e manejo clínico de uma síndrome muito rara

ABSTRACT Shprintzen-Goldberg craniosynostosis syndrome, characterized by craniosynostosis and marfanoid habitus, is a very rare entity described in 75 individuals worldwide. This study aimed to present a case report of a 6-year-old female Brazilian child with Shprintzen-Goldberg's craniosynostosis syndrome. We described the craniofacial and oral characteristics and its clinical management, comparing to the existing literature. The patient presented with intellectual disability, craniosynostosis, ocular proptosis, low-set anomalous ears, and other skeletal and connective tissue defects. Oral features included malocclusion, micrognathia, pseudo-cleft palate, dental caries, and inefficient biofilm control. The treatment started with guidance on cariogenic foods, oral hygiene, and an indication to discontinue bottle feeding. Subsequently, the carious lesions were restored with composite resins, and the patient was referred for orthopedic surgery, orthodontic treatment, speech therapy, and nutritional counseling. The patient was followed for 5 years. This case report emphasizes the importance of knowing the craniofacial and oral characteristics for the diagnosis and clinical management of a female child with a rare Shprintzen-Goldberg's craniosynostosis syndrome. The case also highlights the need for oral health care in individuals with intellectual disabilities.

RESUMO A síndrome Shprintzen-Goldberg é uma entidade muito rara descrita em 75 pessoas, caracterizada por craniossinostose e habitus marfanóide. O objetivo deste estudo é apresentar o relato de um caso clínico de uma criança brasileira de 6 anos com síndrome da craniossinostose de Shprintzen-Goldberg, apresentando as características craniofaciais e orais e seu manejo clínico, comparando com a literatura. O paciente apresentava deficiência intelectual, craniossinostose, proptose ocular, orelhas anômalas de implantação baixa e outros defeitos esqueléticos e do tecido conjuntivo. As características orais incluíram má oclusão, micrognatia, pseudo fenda palatina, atividade de cárie e controle ineficiente do biofilme. O tratamento foi iniciado com orientações sobre alimentos cariogênicos, higiene oral e indicação de suspensão do uso de mamadeira. Em seguida, as lesões cariosas foram restauradas com resina composta e o paciente encaminhado para cirurgia ortopédica, tratamento ortodôntico, fonoaudiologia e nutricionista. O paciente foi acompanhado periodicamente por 5 anos. Este relato de caso enfatiza a importância do conhecimento das características craniofaciais e orais para o diagnóstico e manejo clínico de uma criança do sexo feminino com síndrome de craniossinostose de Shprintzen-Goldberg rara, destacando a necessidade de cuidados com a saúde bucal em indivíduos com deficiência intelectual.

Mandible bone density in adolescents with cerebral palsy using antiepileptic drugs / Densidade óssea da mandíbula em adolescentes com paralisia cerebral em uso de drogas antiepilépticas

Objective: The aim of this study was to assess the bone density of the mandible in adolescents with cerebral palsy (CP) treated with antiepileptic drugs using one beam computed tomography (CBCT). Methods: The study was carried out with 18 adolescents aged 12­18 years, undergoing routine dental treatment at the dental clinic of APCD-São Caetano do Sul. CBCT scans were of divided into two groups: G1 adolescents with CP using antiepileptic drugs and G2 normoactive adolescents. A single dentomaxillofacial radiologist assessed and evaluated the images using Dental Slice software and Image J. Fisher's exact tests as well as paired and unpaired Student's t-tests were performed. Results: Groups differed significantly with regard in the values of density (p < 0.001), with G1 presenting lower values compare to G2. G1 showed significantly lower density means on the right side, left side, and right/left sides of the mandible edge than G2 (p < 0.001). Conclusion: CP patients using antiepileptic drugs show evidence of bone mineral density loss of the mandible.(AU)

Objetivo: O objetivo deste estudo foi avaliar a densidade ótica óssea da mandíbula em adolescentes com paralisia cerebral (PC) tratados com drogas antiepilépticas por meio de tomográfica computadorizada de feixe cônico (TCFC). Métodos: O estudo foi realizado com 18 adolescentes de 12 a 18 anos, em tratamento odontológico de rotina na clínica odontológica da APCD-São Caetano do Sul. As TCFC foram divididas em dois grupos: G1 adolescentes com PC em uso de antiepilépticos e G2 adolescentes normoativos. Um único radiologista dentomaxilofacial assessou e avaliou as imagens usando usando os softwares Dental Slice e Image J. Os testes exatos de Fisher, bem como os testes t de Student pareados e não pareados foram realizados. Resultados: Os grupos diferiram significativamente quanto aos valores de densidade óptica (p <0,001), com o grupo G1 apresentando valores menores em relação ao G2. O grupo G1 apresentou médias de densidade óptica significativamente menores nos lados direito, esquerdo e direito / esquerdo da borda da mandíbula do que o G2 (p <0,001). Conclusão: Pacientes com PC em uso de drogas antiepilépticas apresentam evidências de perda de densidade óssea da mandíbula (AU)

Epidemiological profile of patients with disabilities undergoing dental treatment under general anesthesia / Perfil epidemiológico de pacientes com deficiência submetidos a tratamento odontológico sob anestesia geral

Introduction General anesthesia is commonly used in the dental treatment of people with disabilities, anxious or difficult behavior, who need complex and/or extensive treatments. Objective The aim of this study was to evaluate the epidemiological profile of patients with disabilities undergoing dental treatment under general anesthesia by the team of the Dental Unit for Patients with Special Needs of the Federal University of Sergipe. Material and method Through the analysis of 371 dental records of patients assisted between August 2002 and March 2019. Result The analysis showed that 56.1% of patients were male, the most prevalent age group was 11-20 years, and the most frequent medical conditions were intellectual disability, followed by multiple disabilities. Relative to dental procedures, in 94.1% of the patients, it was observed that 4,056 dental extractions were performed and in 52.3% of patients, 1,156 restorations were performed. In 30.2% of patients, total multiple extractions were performed. Radiographic examination was performed in 51.8% of patients. As regards the origin of patients, 58.8% were from municipalities in the state, other than the capital. Return to the service for follow-up and prevention was observed in 38.5% of patients. Conclusion There is great need for early dental intervention, with specific preventive actions for this group of patients, focusing on those from interior regions of the state.

Introdução A anestesia geral é comumente utilizada no tratamento odontológico de pessoas com deficiência, ansiosos ou com difícil comportamento, que necessitem de tratamentos complexos e/ou extensos. Objetivo Avaliar o perfil epidemiológico da pessoa com deficiência submetida a tratamento odontológico sob anestesia geral pela equipe da Unidade de Odontologia para Pacientes com Necessidades Especiais da Universidade Federal de Sergipe. Material e método Através da análise de 371 prontuários de pacientes assistidos entre agosto de 2002 e março de 2019. Resultado Observou-se que 56,1% dos pacientes eram do sexo masculino, que a faixa etária mais prevalente foi de 11-20 anos de idade e que as condições médicas mais frequentes foram a deficiência intelectual, seguida pelas múltiplas deficiências. Quanto aos procedimentos odontológicos, observou-se que em 94,1% dos pacientes foram realizadas 4.056 extrações dentárias e em 52,3% dos pacientes 1.156 restaurações. Em 30,2% dos pacientes foram realizadas extrações múltiplas totais. O exame radiográfico foi realizado em 51,8% dos pacientes. Em relação a procedência dos pacientes, 58,8% eram provenientes de outros municípios do estado, distinto da capital. Os retornos ao serviço para acompanhamento e prevenção foi observado em 38,5% dos pacientes. Conclusão Há uma grande necessidade de intervenção precoce da odontologia, com ações preventivas específicas para esse grupo de pacientes, com enfoque no interior do estado de Sergipe.

Dental care for children with Congenital Zika Syndrome / Atendimento odontológico de crianças com Síndrome Congênita do Vírus Zika

ABSTRACT There was a large increase in the number of newborns with microcephaly in Brazil between 2015 and 2017, mainly in the Northeast. This increase was associated with intrauterine Zika virus infection, which causes a congenital syndrome characterized by neurological, musculoskeletal, and sensory abnormalities. Despite the great worldwide repercussion, few studies about oral conditions in children with the syndrome have been published. This work aims to propose a guide for the dental care of these individuals on the basis of a literature review. Children with congenital Zika syndrome have a number of systemic comorbidities that affect their oral health and can compromise dental care. To date, no clinical protocol has been established for the dental care of children with congenital Zika syndrome. This is a pioneering study of great importance to orient dental professionals and promote the dental health of these children.

RESUMO Entre 2015 e 2017, houve um grande aumento no número de notificações de recém-nascidos com microcefalia no Brasil, principalmente na região Nordeste. Essa ocorrência foi associada ao vírus Zika, o qual foi responsável por uma síndrome caracterizada por problemas neurológicos, musculoesqueléticos, sensoriais, entre outros, denominada Síndrome Congênita do Vírus Zika. Apesar da grande repercussão mundial, poucos estudos acerca do comprometimento oral nessas crianças foram publicados. Dessa forma, este trabalho tem como objetivo propor a partir de uma revisão de literatura, um referencial de orientação para o atendimento odontológico destes indivíduos, a fim de embasar os profissionais dessa área. Observou-se que pessoas com Síndrome Congênita do Vírus Zika apresentam uma série de comorbidades sistêmicas que influenciam na sua condição oral e podem comprometer o atendimento odontológico, necessitando de cuidados especiais. Até então, nenhum protocolo clínico para o atendimento dessas crianças foi encontrado na literatura. Dessa forma esse estudo é pioneiro e de grande importância para direcionamento profissional e cuidado desses pacientes.

Inflammatory markers in the saliva of cerebral palsy individuals with gingivitis after periodontal treatment

Abstract The aim of this study was to evaluate the effect of periodontal treatment on the salivary cytokine levels and clinical parameters of individuals with cerebral palsy (CP) with gingivitis. A non-randomized, clinical trial was conducted in individuals diagnosed with spastic CP. Thirty-eight individuals were enrolled in the study and were categorized according to gingival index scores between 0-1 or 2-3, assigned to groups G2 or G1, respectively. Periodontal treatment comprised oral hygiene instructions, conventional mechanical treatment and 0.12% chlorhexidine applied as an adjunct. Clinical parameters and saliva samples were collected at baseline and at the 15-day follow-up visit. Bleeding on probing and periodontal screening and recording were determined. Non-stimulated saliva samples were obtained, and the salivary flow rate, the osmolality and the levels of cytokines IL-1β, IL-6, IL-8, IL-10, TNF-α and IL-12p70 were evaluated by a cytometric bead array. The Wilcoxon test, the Mann-Whitney test, Spearman correlation analysis, Poisson regression analysis and an adjusted analysis were performed (α = 0.05). The groups differed significantly in periodontal clinical parameters at baseline and at follow-up. Salivary flow rate and osmolality were similar in both groups at both timepoints. However, TNF-α and IL-1β levels were higher in G1 than in G2 at baseline. Mechanical treatment resulted in improved clinical parameters for both groups. Furthermore, mechanical treatment resulted in a significant reduction in salivary IL-1β and IL-8 levels for both groups after treatment. Periodontal treatment performed in individuals with CP and gingivitis reduces the levels of TNF-α, IL-1β, IL-6 and IL-8.

Correlation of salivary immunoglobulin A with Body Mass Index and fat percentage in overweight/obese children

Abstract Obesity is considered a risk factor for periodontal health due to the low- grade inflammation promoted by the increased adipose tissue. Objective: This study aimed to determine correlations and associations between gingival inflammation (Simplified Oral Hygiene Index, and Gingival Index), salivary immunoglobulin A (s-IgA), and salivary parameters (salivary flow and osmolality) in normal-weight and overweight/obese children. Material and Methods: Ninety-one children, aged 6 to 12 years old (8.6±1.9 years), were divided into two groups according to their body mass index (BMI), circumferences, skinfold measurements and body fat percentage: normal- weight group (NWG; n =50) and overweight/obese group (OG; n =41). A calibrated examiner performed the clinical examination using the Simplified Oral Hygiene Index, Gingival Index, and salivary collection. Data analysis included descriptive statistics and association tests ( p <0.05). Results: OG presented statistically higher s-IgA values compared with NWG, especially among the obese children ( p <0.05). Significant positive correlations between s-IgA and salivary osmolality in OG ( p <0.05), and between s-IgA and BMI values ( p <0.05) and body fat percentage ( p <0.05) were observed among all the children. Effect size varied from moderate for s-IgA values ( d =0.57) to large for BMI ( d =2.60). Conclusion: Gingival inflammation and salivary parameters were similar for NWG and OG; however, s-IgA presented higher values in OG, with correlations between BMI and body fat percentage.

Barriers to Access to Dental Treatment for People with Physical Disabilities in a Brazilian Metropolis

Objective: To evaluate the barriers for accessing dental care for people with physical disabilities. Material and Methods: A cross-sectional study with 191 caregivers of individuals with physical disabilities attending a rehabilitation center in São Paulo, who responded to a questionnaire about information related to barriers (user, caregiver, government and professional) found in dental treatment, visit to the dentist and age of the first dental appointment. Data were collected from medical records regarding age, sex, family income and medical diagnosis of patients. Statistical analysis was performed using the MedCalc for Windows software version 12.3.0. The Chi-square test was applied for heterogeneity, with significance level of 5%. Results: The main barriers identified by caregivers (p<0.0001) were patient fear/anxiety (66.8%), patient requiring accompaniment to access treatment (87.4%), treatment costs (82.7%), lack of treatment at primary health care units (73.3%) and professionals not specialized in dental care for people with physical disabilities (67.0%). It was observed that caregivers of individuals with cerebral palsy reported greater physical barriers for accessing dental treatment compared to caregivers of other diagnoses (p=0.0307). Conclusion: Individuals with physical disabilities face financial constraints, fear of dental treatment, lack of treatment options in public services and, perhaps most importantly, lack of qualified professionals interested in treating such individuals.

Prevalência de traumatismos dentários em pacientes com distúrbio neuropsicomotor: estudo controlado / Prevalence of tooth injuries in patients with neuropsychomotor disorder

Introdução: Lesões dentárias por trauma constituem experiências angustiantes em crianças, que promovem alterações tanto físicas quanto emocionais e psicológicas. Objetivo: Avaliar a prevalência de traumatismos dentários em pacientes com distúrbio neuropsicomotor e comparar a indivíduos normorreativos. Material e método: Avaliaram-se 120 indivíduos, sendo 60 com alterações neuropsicomotoras (grupo de estudo) e 60 normorreativos (grupo controle), de ambos os sexos, de 2 a 15 anos de idade, assistidos na Fundação de Apoio ao Deficiente do Governo do Estado da Paraíba. Os dados foram coletados por meio de questionário estruturado e exame clínico. Foi realizada análise descritiva e inferencial (teste t-student; teste Exato de Fisher), adotando-se um nível de significância de 5%. Resultado: A prevalência de traumatismos dentários observada em pacientes com distúrbio neuropsicomotor foi de 20,0%, enquanto que no grupo controle foi de 16,6% (p>0,05); no grupo controle a ocorrência foi maior no sexo masculino. Os grupos diferiram quanto ao tipo de atividade no momento do trauma (p<0,05) em relação à etiologia (p<0,05) e em relação ao local de ocorrência (p<0,05). Para ambos os grupos, os dentes mais afetados foram os incisivos centrais superiores. As fraturas de esmalte, seguidas pelas de esmalte e dentina sem exposição pulpar foram as lesões mais comuns nos dois grupos. Conclusão: A prevalência de traumatismos dentários em indivíduos com alteração neuropsicomotora é similar à de indivíduos normorreativos, com maior ocorrência no sexo feminino, em fase anterior à adolescência, durante atividades de rotina.

Introduction: Traumatic dental injuries are distressing experiences in children, which promote both physical, emotional and psychological changes. Objective: To evaluate the prevalence of dental trauma in patients with neuropsychomotor disorder and to compare to normoreactive individuals. Material and method: 120 individuals, 60 neuropsychomotor changes (study group) and 60 normorreatives (control group), of both sexes, from 2 to 15 years old, assisted in the Foundation of Support to the Disabled of the Government of the State of Paraíba. Data were collected through a structured questionnaire and clinical examination. Descriptive and inferential analysis (t-student test; Fisher's exact test) was performed, adopting a significance level of 5%. Result: The prevalence of dental trauma observed in patients with neuropsychomotor disorder was 20.0%, whereas in the control group it was 16.6% (p>0.05); in the control group the occurrence was higher in males. The groups differed according to the type of activity at the moment of the trauma (p<0.05) in relation to the etiology (p<0.05), and in relation to the place of occurrence (p<0.05). For both groups, the most affected teeth were the maxillary central incisors. Enamel fractures, followed by enamel and dentin fractures without pulp exposure were the most common lesions in both groups. Conclusion: The prevalence of dental trauma in individuals with neuropsychomotor alterations is similar to that of normorreative individuals, with a higher occurrence in females, in preteen phase, during routine activities.

Sobrecarga dos cuidadores de crianças e adolescentes com Síndrome de Down / Burden of caregivers of children and adolescents with Down Syndrome

Resumo O objetivo foi avaliar o perfil e a sobrecarga de cuidadores de crianças/adolescentes com e sem síndrome de Down. As avaliações foram realizadas por meio dos questionários sobre o perfil e a sobrecarga dos cuidadores (Burden Interview), e o perfil das crianças/adolescentes. Estes questionários foram aplicados a 168 cuidadores. Os testes Qui-quadrado, Exato de Fisher e Análise de Variância foram empregados com nível de significância fixado em α = 5%. Ambos os grupos eram compostos por 84 participantes, e os cuidadores do grupo com deficiência apresentaram porcentagem significantemente maior para o sexo feminino (p = 0,001), faixa etária de 41-60 anos (p < 0,001), não possuíam ocupação laboral (p < 0,001), baixa renda per capita (p < 0,001), baixo nível de escolaridade (p = 0,021), religião católica (p = 0,001), maiores de problemas de saúde (p < 0,001), em uso de medicação continua (p < 0,001) e com nível de sobrecarga moderada (p < 0,001). As crianças/adolescentes com deficiência necessitavam significantemente maior auxilio para a alimentação (p = 0,051), banho (p = 0,006), vestuário (p = 0,042), controle de esfíncteres (p = 0,027) e higiene íntima (p < 0,001). Os cuidadores de crianças/adolescentes com síndrome de Down apresentam sobrecarga moderada, quando comparados à cuidadores de crianças/adolescentes normoreativas.

Abstract The aim of this study was to evaluate the profile and burden of caregivers of children/adolescents with and without Down syndrome. The evaluations were performed through questionnaires about the profile and burden of the caregivers (Zarit Burden Interview) and the profile of the children/adolescents. These questionnaires were applied to 168 caregivers. The chi-square test, Fisher's exact test, and analysis of variance were used with a significance level set at a = 5%. Both groups were composed of 84 participants, and the caregivers of the disabled group had a significantly higher percentage of females (p = 0.001), those in the 41-60 age group (p < 0.001), those who had no occupation (p < 0.001), those with a low per capita income (p < 0.001), those with a low level of schooling (p = 0.021), those who were Catholic in religion (p = 0.001), those who had more health problems (p < 0.001), those who continued the use of medication (p < 0.001), and those with a moderate level of burden (p < 0.001). The children/adolescents with disabilities needed significantly more help for eating (p = 0.051), bathing (p = 0.006), dressing (p = 0.042), sphincter control (p = 0.027), and intimate hygiene (p < 0.001). The caregivers of children/adolescents with Down syndrome presented a moderate burden compared to the caregivers of normoreactive children/adolescents.

The influence of chemiotherapic agents and their accessories on oral manifestations of acute lymphoid leukemic children

Aim: To evaluate the influence of chemotherapy agents and their accessories on oral manifestations of children who have acute lymphoid leukemia. Material and Methods: After the stipulated period for the research, the total sample reached was of 68children. Nevertheless, only 46 children had continued for the second period. Children from 2 to 12 years of age who had been diagnosed with ALL ­ and would be submitted to treatment at Ophir Loyola Hospital, in Belém, State of Pará ­ had been included in the research. The first evaluation has been held before the chemotherapy treatment and had offered anamnesis and clinical exams. The second evaluation has been held in 10 to 15 days after the beginning of chemotherapy treatment and has offered a new clinical exam and annotations of the drugs which had been utilized during the chemotherapy. Results: From the drugs given at Ophir Loyola Hospital, it has been observed that 14 to 24mg (83%), vincristine 0,6mg to 1 g (80%), ARA-C 20mg to 1600mg (74%), cardioxane13mg to 340mg (65%), methotrexate 12mg to 2400mg (63%), cyclophosphamide 104mg to 1540mg (59%), asparaginase 50UI to 9600UI (57%) andmesna 75mg to 510mg (54%) have been used the most. No drug has presented statistic at 5% levelin Fisher exact test, when crossing with the presence of the main mouth manifestations: mucositis, xerostomia, toothache,and dysphagia. Conclusions: In the face of the results, it can be concluded that there has been no influence of the chemotherapy agents and their accessories in the oral manifestations of acute lymphoid leukemic children; nevertheless, these patients may present any kind of lesion on the mouth cavity during or after the beginning of chemotherapy. The dental surgeon needs to recognize the oral manifestations and intervene on the buccal health of the ALL patients, contributing and helping with his/her treatment.

Alterações fisiológicas e de erupção dentária na obesidade infantil / Physiological alteration and dental eruption in child obesity

A obesidade infantil vem crescendo e se tornando um problema mundial. Na Odontologia, em relação à obesidade infantil, já foram realizados trabalhos tentando mostrar alguma correlação entre doença cárie e doença periodontal com resultados controversos. Em relação à obesidade infantil e à erupção dentária, alguns trabalhos demostraram evidências de interação, que se apresenta precoce nesses casos, sendo importante observar os trabalhos que avaliam tais correlações. O objetivo desta revisão é associar as relações fisiológi¬cas em crianças obesas e a erupção dentária. Existem alguns fatores que podem justificar a ocorrência dessa erupção precoce como alguns hormônios do sistema endócrino, a leptina e os hormônios sexuais em crianças que apresentam obesidade. Outro ponto é a aceleração na puberdade, concomitantemente com fechamento das epífises e crescimento de ossos longos e da face nessas crianças. A pré-disposição à inflamação crônica também pode influenciar no processo de erupção dentária em crianças obesas. Os profissionais envolvidos no atendimento integral de crianças devem avaliar informações importantes como a troca de dentes e a idade estimada para a erupção dos dentes permanentes, a fim de correlacioná-las, por exemplo, a fatores como a obesidade infantil

Child obesity has been increasing and becoming a worldwide problem. In Odontology, regarding to child obesity, studies have been done trying to show a correlation between dental caries and periodontal disease, but they have had controversial results. In relation to child obesity and dental eruption, studies ­ that should be referred to ­ have provided evidence of interaction between them, which appears at early stages in these cases. This revision aims at associating the physiological relations in obese children and dental eruption. There are some factors that can justify the occurrence of these precocious eruptions such as a few hormones from the endocrine system, leptin, and sexual hormones in obese children. Another point is the acceleration in puberty, simultaneously to the closing of the epiphysis and the growth of long bones and of these children's faces. The pre-disposition to chronic inflammation can also influence the process of dental eruption in obese children. The professionals involved in the full care of children must assess important information, such as tooth change and the estimated age for the eruption of permanent teeth, in order to correlate it to factors such as child obe¬sity, for instance

Pediatric cancer: epidemiologic profile of attended children in a reference center in the state of Para

Aim: To describe the epidemiological findings of children diagnosed with cancer in a referral center. Material and Methods: Daily at Ophir Loyola Hospital visits were made - Belém / PA, in clinical pediatric oncology sector, from December 2013 to June 2014. The sample comprised 46 children 2-12 years, diagnosed with cancer, which was already or would begin anticancer treatment. A questionnaire containing questions about family, socioeconomic and environmental aspects was applied.. Results: The most frequent neoplasia LLA was followed by nephroblastoma, neuroblastoma, Hodgkin lymphoma, and osteosarcoma. The genre most affected by childhood cancer was male. The age group with the predominant prevalence were children aged 8-12 years. By observing the religious belief that it was possible to detect most practiced Catholicism. The practice of sports is not part of the daily lives of these children. The origin of these families had dominated for deriving from the state. As the rating distribution of households according to the Economic Classification Criterion Brazil, the two classes were most frequently C2 and D. Conclusions: We sought, in this article, to demonstrate the epidemiological profile of children seen at a referral center in the state of Para. Research like this, identifying population groups at highest risk or with more unfavorable prognosis, provide health authorities and researchers in the area of cancer with an important instrument in the definition of health necessary for proper control and prevention of the disease.

Manifestações bucais e uso de serviços odontológicos por indivíduos com doença renal crônica / Oral manifestations and use of dental care assistance by individuals with chronic kidney disease

Objetivo: Avaliar as manifestações bucais e o uso de serviços odontológicos de indivíduos com Doença Renal Crônica (DRC) em tratamento hemodialítico. Materiais e Métodos: Participaram doestudo 130 indivíduos, de ambos os sexos e com idade superior a 18 anos em atendimento no Serviço de Hemodiálise de referência da cidade de João Pessoa-PB. Foram coletados dados socioeconômicos,saúde geral, higiene bucal, autopercepção dos problemas bucais e acesso ao serviço odontológico. Um único examinador realizou o exame clínico intrabucal. Resultados: A maioria dos participantes era do sexo masculino (60,8%), com baixos níveis de escolaridade (56,9%) e renda(61,5%). Houve o predomínio da hipertensão arterial sistêmica (86,2%) na doença de base. Em relação à autopercepção dos problemas bucais, os participantes relataram com maior frequência axerostomia (51,5%), seguida de mau hálito (30,0%). Dentre as manifestações bucais, a gengivite e a presença de cálculo dentário foram as mais prevalentes, com 66,2% e 56,2%, respectivamente.A maioria dos indivíduos buscava atendimento odontológico na rede pública de saúde e afirmava que o cirurgião-dentista não estava preparado para atender e explicar o tratamento que seria realizado. Conclusão: As principais alterações bucais identificadas foram xerostomia, mau hálito,cálculo dentário e gengivite, e que a maioria dos indivíduos tinha dificuldade no acesso ao serviço odontológico público de saúde.

Objective: To assess oral manifestations and use of dental care assistance by individuals with Chronic Kidney Disease (CKD) in hemodialysis treatment. Materials and Methods: Participated inthe study 130 individuals of both genders and aged over 18 years old attending the Hemodilalysis Reference Service in João Pessoa - PB. Data collection for socioeconomic status, oral hygiene, self--awareness of oral problems and access to dental care was carried out. A single examiner ran a clinical intraoral exam. Results: Most participants were male (60.8%) with low levels of education(56.9%) and income (61.5%). There was a predominance of systemic arterial hypertension (86.2%)as the underlying disease. In relation to the self-awareness of oral problems, participants reporteddry mouth most frequently (51.5%) followed by bad breath (30.0%). Among oral manifestations, gingivitis and the presence of tartar were the most prevalent, 66.2% and 56.2%, respectively. Mostindividuals sought dental care in the public health system and stated that the dental surgeon wasnot prepared to attend and explain the treatment to be provided. Conclusion: The main oral alterationsidentified were dry mouth, bad breath, tartar as well as gingivitis, and that most participantsfound it difficult to have access to dental care assistance in the public health system.

Estudo comparativo entre enzimas utilizadas no metabolismo de medicamentos em pacientes com paralisia cerebral e anestésicos odontológicos / Comparative study of the enzymes involved in drug metabolism in patients with cerebral palsy and dental anesthetics

A administração conjunta de dois ou mais fármacos é uma situação comum na prática clínica e pode criar efeitos terapêuticos indesejados. Podem surgir interações como alteração na biotransformação através de enzimas microssomais criando metabólitos tóxicos. O objetivo deste estudo foi comparar enzimas microssomais utilizadas no metabolismo de medicamentos de uso contínuo em pacientes com PC e anestésicos locais. Esta pesquisa é um estudo quantitativo com abordagem descritiva, realizado através de coleta de dados de prontuários de pacientes em tratamento no Lar Escola São Francisco (LESF) em parceria com a Universidade Cruzeiro do Sul (UNICSUL). Foram avaliados prontuários de pacientes com paralisia cerebral independente do sexo, idade e tipo de paralisia cerebral. A amostra foi constituída de 348 prontuários examinados, sendo 147 (42,2,%) do sexo feminino e 201 (57,8%) pacientes do sexo masculino. A idade variou de 5 a 16 anos (média = 9,6 DP±5,4). Do total da amostra, 79% necessitavam de tratamento odontológico, com anestesia local. Quanto ao uso de medicamentos, 170 (49%) da amostra faziam uso de medicamentos neurolépticos. Concluiu-se que o cuidado na co-administração de lidocaína, anestésico local empregado na Odontologia e drogas anticonvulsivantes, diminuirá os riscos de hepatotoxocidade, uma vez que ambos utilizam a mesma enzima microssomal. Assim, sugere-se o uso de sais anestésicos que utilizem outro citocromo como P450 CYP1A2, dentre eles a mepivacaína, articaína e bupvacaína...

Co-administration of two or more drugs is a common situation in clinical practice that can promote undesirable therapeutic effects. Interactions may occur, such as changes in biotransformation in which microsomal enzymes produce toxic metabolites. This study compared microsomal enzymes used in the metabolism of drugs in continuous use in patients with CP and local anesthetics. The research is a quantitative study with a descriptive approach conducted by collecting data from medical records of patients at the Lar Escola São Francisco (LESF) in partnership with the Cruzeiro do Sul University (UNICSUL). Records of patients with cerebral palsy were evaluated regardless of sex, age, and type of cerebral palsy. The sample consisted of 348 records, of which 201 (57.8%) were males. Patient age ranged from 5 to 16 years-old (mean = 9.6, SD ±5.4). Of the total sample, 79% required dental treatment under local anesthesia. Regarding drug use, 170 (49%) of the sample were being administered neuroleptic drugs. It was concluded that the caution in lidocaine co-administration, a local anesthetic applied in Dentistry, and anticonvulsants, will decrease the risks of hepatotoxicity, seeing that both use the same microsomal enzyme. It is suggested the use of anesthetics that utilized other cytochrome as P450 CYP1A2, among them mepivacaine, articaine, and bupivacaine...

Does the classification of cerebral palsy influence caries experience in children and adolescents?

To evaluate the influence of the classification of cerebral palsy CP on the caries experience in children and adolescents, and determine the types of teeth most affected by dental caries. METHODS: A total of 181 individuals with CP, aged 8.30±4.10 years were examined for dental caries diagnosis in primary, mixed and permanent dentitions. The sample consisted of 96 quadriplegic individuals, 56 diplegic, 18 hemiplegic and 11 with choreoathetosis. The groups were compared using Kruskal-Wallis and Chi-square tests. Univariate logistic regression models were used to identify whether age was a predictor of caries risk α=5%. RESULTS: The sample was homogeneous as regards sex and age, among patients with quadriplegia, diplegia, hemiplegia and choreoathetosis. Out of the total sample, 51.4% of the individuals were caries free. The overall mean for the dmft and DMFT indices were 1.70±3.30 and 0.70±1.60, respectively. The mean caries experience in primary, mixed and permanent dentitions did not vary significantly according to the CP classification p>0.05. Child´s age was a predictor for dental caries experience p<0.05. CONCLUSIONS: The CP classification did not influence on caries experience, and the teeth most affected by dental caries were the primary and first permanent molars...

Efeito da fotobiomodulação no músculo masseter de criança com paralisia cerebral: relato de caso / Photobiomodulation effect on the masseter muscle in children with cerebral palsy: a case report

A espasticidade acarreta hipertonia nos músculos mastigatórios dos indivíduos com paralisia cerebral (PC), interferindo na amplitude de abertura bucal, dificultando a realização da higiene oral predispondo estes indivíduos a condições consideradas de risco para o desenvolvimento de doenças bucais. Objetivo: Avaliar o efeito da fotobiomodulação com laser de diodo, de baixa intensidade na espessura do músculo masseter em uma criança com PC do tipo espástico. Método: O relato do cuidador era que a criança apresentava grande dificuldade na realização da higiene bucal e com movimentos de fuga da cabeça quando a escova dental tocava a região de molares superiores. Com relação ao desconforto da criança, a mãe referiu como extremo. A 1ª avaliação ultrassonográfica foi realizada na avaliação inicial, e a 2ª avaliação após 6 sessões de aplicação de fobioestimulação. Foi empregado o Laser infravermelho, de Diodo, de baixa intensidade, As-Ga-Al, (? = 808 ± 3 nm, 120 mW; Twin Flex Evolution Laser MMOptics São Paulo, Brazil), usando 5,0 J/cm2 energia dose/local, com 20 segundos de exposição/local. A área do músculo masseter irradiado bilateralmente foi o ponto médio no sentido da sua extensão e largura. Foram realizadas seis sessões, com intervalo de 7 dias entre elas. Resultados: Ao final da sexta sessão da fotobioestimulação, a responsável relatou que a criança dormia melhor, apresentava redução no número de movimentos involuntários realizados pela mandíbula e a realização da higiene bucal era possível sem expressão dolorosa da criança. Durante a palpação observou-se menor hipertonia em masseter bilateral, ganho em espessura, e aumento na distância inter-incisal de 7 mm. Conclusão: A fotobioestimulação com laser de diodo parece ser efetiva na redução da espasticidade no músculo masseter de crianças com PC do tipo espástico

Spasticity causes stiffness in the masticatory muscles of individuals with cerebral palsy (CP), affecting the amplitude of mouth opening, making oral hygiene conditions difficult and predisposing these individuals to the risk of developing oral diseases. Objective: To evaluate the effect of a low-intensity photobiomodulation diode laser on the thick part of the masseter muscle in a child with spastic type CP. Method: The caregiver reported that the child had great difficulty in performing the oral hygiene, making avoidance movements of the head when the toothbrush touched the mucosa of the upper molar region in the mouth. The mother described the child's discomfort as extreme. The first ultrasound evaluation was performed at the first appointment, and the second evaluation after 6 sessions of photobiostimulation. The low-intensity Infrared Laser Diode, Ga-As-Al, was employed (? = 808 ± 3 nm, 120 mW; Twin Flex Evolution Laser MMOptics São Paulo, Brazil), using 5.0 J/cm2 dose energy/location, with 20 seconds exposure/site. The area of the masseter muscle was bilaterally irradiated towards the midpoint of its length and width. Six sessions were performed, with an interval of 7 days between them. Results: At the end of the sixth session of photobiostimulation, the mother reported that the child slept better, had reduction in involuntary movements performed by the jaw, and oral hygiene was possible now with no painful expression of the child. During palpation there was less stiffness in the bilateral masseter and an increased masseter thickness and increase in the amplitude of the mouth opening of 7 mm. Conclusion: The diode laser photobiostimulation appears to be effective in reducing spasticity in the masseter muscle of children with spastic type CP

Avaliação da microdureza do esmalte de dentes decíduos de crianças com paralisia cerebral / Enamel microhardness of primary teeth of cerebral palsy children

Introdução: Em indivíduos com paralisia cerebral, ocorre redução do fluxo salivar, o que pode predispor à hipomineralização do esmalte e à cárie dentária. Objetivo: Comparar a microdureza do esmalte de dentes decíduos anteriores e posteriores de crianças com paralisia cerebral (PC) e crianças normorreativas (NR). Material e Método: Foram utilizados 58 dentes decíduos esfoliados/extraídos, que foram distribuídos em quatro grupos: (A) anteriores de PC (n=14); (B) anteriores de NR (n=16); (C) posteriores de PC (n=14), e (D) posteriores de NR (n=14). Os dentes foram seccionados, incluídos em resina acrílica, lixados e polidos. A análise da microdureza longitudinal foi realizada em microdurômetro com endentador do tipo Knoop, com carga estática de 25 g/f e tempo de 5 segundos. Foram realizadas três fileiras de 12 endentações, distanciadas entre si em 100 mm, com profundidade entre 10 e 180 mm. Foram obtidas as médias de cada profundidade para cada dente e, posteriormente, as médias de cada profundidade para cada grupo avaliado. O teste estatístico empregado foi o de Mann-Whitney (α=5%)). Resultado: As médias de microdureza foram 253,5 ± 55,3 (A), 247,6 ± 45,7 (B), 284,4 ± 68,7 (C) e 252,2 ± 53,8 (D). Não houve diferença estatisticamente significante entre os grupos A e B e os grupos C e D, para cada profundidade e para a média global (p>0,05). Conclusão: Pôde-se concluir que a microdureza de esmalte de dentes decíduos anteriores e posteriores de crianças com PC foi semelhante à microdureza de esmalte de dentes decíduos de crianças normorreativas. .

Introduction: Cerebral palsy subjects present reduced salivary flow, which may predispose to enamel hypomineralization and dental caries. Aim: To compare the enamel microhardness of anterior and posterior primary teeth of normorreactive children (NR) and children with cerebral palsy (CP). Material and Method: The sample was consisted of 58 exfoliated/extracted primary teeth distributed into 4 groups: (A) anterior teeth of CP (n= 14), (B) anterior teeth of NR (n=16),(C) posterior teeth of CP (n=14) and (D) posterior teeth of NR (n=14). The teeth were hemisectioned, embedded in acrylic resin, grounded and polished. The longitudinal microhardness analysis was carried out in a microdurometer with a Knoop indenter with a 25-gram load for 5 seconds. Three rows of 12 indentations were made from the outer surface from 10 to 180 mm. The rows were spaced 100 mm from each other. The values of the three measurements at each distance were averaged for each tooth and, afterwards, for each group. The non-parametric statistical test used was the Mann-Whitney U (α=5%). Result: The microhardness means data were 253.5 ± 55.3 (A), 247.6 ± 45.7 (B), 284.4 ± 68.7 (C) and 252.2 ± 53.8 (D).There was no significant difference between the groups A and B, as well as groups C and D for each distance and global average (p>0.05). Conclusion: It can be concluded that the enamel microhardness of anterior and posterior primary teeth of cerebral palsy children was similar to the normorreactive children. .

Frenectomia labial em paciente com síndrome de Cornelia de Lange / Labial frenectomy in patient with Cornelia de Lange syndrome

Síndrome de Cornelia de Lange é uma anormalidade de desenvolvimento multisistêmica caracterizada por retardo cognitivo e de crescimento; dismorfia craniofacial, malformações dos membros superiores; disfunção geniturinária e oftalmológica, hirsutismo e anomalias cardíacas e gastroesofágicas. Cílios longos e sobrancelhas arqueadas com sinófiris, filtro longo com lábio superior fino. Ponte nasal deprimida com narinas antevertidas também ocorre com frequência. Problemas dentários são frequentes e incluem: palato ogival, micrognatia, atraso na erupção, erosão dental, doença gengival e periodontal. Com base nessas observações, o presente estudo tem como objetivo descrever a frenectomia labial em um paciente com síndrome de Cornelia de Lange, de 19 anos de idade, gênero masculino, bem como as recomendações para o manejo clínico e controle do biofilme dental

Cornelia de Lange syndrome is an abnormality multisystem developmental characterized by cognitive and growth retardation; craniofacial dysmorphia, malformations of the upper extremities, genitourinary and ophthalmologic dysfunction, hirsutism, cardiac and gastroesophageal abnomalies. Long eyelashes, arched eyebrows with synophrys, long philtrum with thin upperlip. Depressed nasal bridge with anteverted nares also frequently occur. Dental problems are common and include: high palate, micrognathia, delayed eruption, dental erosion, gingival and periodontal disease. Based on these observations, the present study aims to describe the labial frenectomy in a patient with Cornelia de Lange syndrome, 19 years old, male gender, as well as recommendations for the clinical management and control of dental biofilm